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042780 Rabbit Anti-Tgfbr1, ID (Tgfbr1, TGF-beta receptor type-1, ESK2, Transforming growth factor-beta receptor type I)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Swiss Prot
Q64729
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Mo
Accession #
NP_033396.1
Gene ID
21812
Gene #
Tgfbr1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Tgfbr1, TGF-beta receptor type-1, ESK2, Transforming growth factor-beta receptor type I

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Mouse Tgfbr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-169 amino acids from the Central region of Mouse Tgfbr1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Mouse
References
Ghoreschi, K., et al. Nature 467(7318):967-971(2010)|Kel, J.M., et al. J. Immunol. 185(6):3248-3255(2010)|Droguett, R., et al. Exp. Cell Res. 316(15):2487-2503(2010)|Moreno, S.G., et al. Dev. Biol. 342(1):74-84(2010)|Shimogori, T., et al. Nat. Neurosci. 13(6):767-775(2010)
USBio References
No references available
Conjugates
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