KLRC3

Clone Type

Monoclonal

Host

Mouse

Source

Human

Isotype

IgG2a,k

Clone Number

3D5

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Accession #

NM_002261, NP_002252

Shipping Temp

Blue Ice

Storage Temp

-20°C

Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.

Applications

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution

Optimal dilutions to be determined by the researcher.

AA Sequence

GKERRTWEESLQACASKNSSSLLSIDNEEEMKFLASILPSSWIGVFRNSSHHPWVTINGLAFKHEIKDSDHAERNCAMLHVRGLISDQCGSSRIIRRGFIMLTRLVLNS

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

Partial recombinant corresponding to aa132-240 from human KLRC3 (NP_002252) with GST tag. MW of the GST tag alone is 26kD.

Form

Supplied as a liquid in PBS, pH 7.2.

Purity

Purified by Protein A affinity chromatography.

Specificity

Recognizes human KLRC3.

References

1. Glycosylation-related gene expression is linked to differentiation status in glioblastomas undifferentiated cells. Cheray M, Petit D, Forestier L, Karayan-Tapon L, Maftah A, Jauberteau MO, Battu S, Gallet FP, Lalloue F.Cancer Letters (2011), doi: 10.1016/ j.canlet.2011.07.027

USBio References

No references available

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128901 Mouse Anti-KLRC3 (NKG2-E Type II Integral Membrane Protein, NK Cell Receptor E, NKG2-E-activating NK Receptor, NKG2E)

Clone Type

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Clone Number

Grade

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Crossreactivity

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References

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