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C2432-01E Mouse Anti-CD80 (T-lymphocyte Activation Antigen CD80, Activation B7-1 Antigen, BB1, CTLA-4 Counter-receptor B7.1, B7, CD28LG, CD28LG1, LAB7)

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Isotype
IgG1
Clone Number
P1.H5.A1.A1
Grade
Affinity Purified
Applications
E FC
Crossreactivity
Hu
Shipping Temp
Blue Ice
Storage Temp
-20°C

Human CD80 (B7-1) is a costimulatory ligand for CD28 and CTLA-4. CD80 is expressed on activated B cells.

Functional Application: Antibody blocks binding of soluble CD152 Ig fusion protein to CD80.
Applications
Suitable for use in Flow Cytometry and ELISA. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
Human CD80 (B7-1) Ig Fusion Protein
Form
Supplied as a liquid in PBS, pH 7.2, 0.5mg/ml gentamicin sulfate.
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes the CD80 molecule.
References
1. C.B. Thompson, (1995) Cell 81: 979-982. |2. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 682-684.
USBio References
No references available
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