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366909 Pyrintegrin CAS: 1228445-38-2

Specifications
References
CAS Number
1228445-38-2
Grade
Highly Purified
Molecular Formula
C23H25N5O3S
Molecular Weight
451.5
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
N-(cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]- benzenesulfonamide

Pyrintegrin is a Beta1 integrin activator that also activates a variety of other growth factor receptors. It is reported to aid in the survival of human embryonic stem cells after trypsin dissociation and enhance their adhesion to laminin and matrigel plates.

Synonyms
N-(cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]- benzenesulfonamide
Molecular Formula
C23 H25 N5O3
Molecular Weight
451.5
CAS Number
1228445-38-2
Purity
≥95%
Applications
FA
Appearance
Crystalline solid
Solubility
Soluble in organic solvents such as ethanol and DMSO. DMSO up to 65mM.
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
1. Shah, B. S. (2012). Pyrintegrin Induced Adipogenesis: Biology (Doctoral dissertation, Columbia University). 2. Lee, H. W., Khan, S. Q., Faridi, M. H., Wei, C., Tardi, N. J., Altintas, M. M., ... & Gupta, V. (2015). A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules.  Journal of the American Society of Nephrology, ASN-2014090859. 3. Li, W., & Ding, S. (2011). Human pluripotent stem cells: decoding the naive state. Science translational medicine, 3(76), 76ps10-76ps10.
USBio References
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