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Anti -4-1BB LIGAND (TNFSF9, 4-1BBL, 4-1BB-L, Tumor necrosis factor ligand superfamily member 9) (Biotin)
Anti -4-1BB LIGAND (TNFSF9, 4-1BBL, 4-1BB-L, Tumor necrosis factor ligand superfamily member 9) (Biotin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
|
| TNFSF9, a type II transmembrane glycoprotein and member of the TNF superfamily, preferentially expressed by B cells, acts as a ligand for CD137 (4-1BB ligand receptor/TNFRSF9). | | | Interaction between 4-1BBL and its receptor acts as a co-stimulatory signal for T cell activation and expansion, and is involved in the generation of cytotoxic T cells (Tc) and in the process of antigen presentation. Expression of 4-1BBL by a variety of carcinoma cells, suggests a role for 4-1BBL in tumor cell-T cell interactions. | | | Catalog # | 0004-01I | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 0.25-1ug/ml | | Western Blot: 0.1-0.2ug/ml | | Optimal dilutions to be determined by the researcher. | | Recommended Secondary Antibodies | Streptavidin APC | | Streptavidin FITC | | Streptavidin TRITC | | Streptavidin RPE, RPE | | Streptavidin HRP | | Streptavidin Alk. Phos. | | Storage and Stability | Lyophilized powder may be stored at-20°C. Stable for 12 months at -20°C. Reconstitute with 0.5ml sterile PBS containing 0.1% BSA. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 0.5ml sterile PBS containing 0.1% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant human 4-1BBL. | | Specificity | Recognizes human 4-1BB Ligand (TNFSF9, 4-1BBL, 4-1BB-L, Tumor necrosis factor ligand superfamily member 9) | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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