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You are here:Home » Antibodies » Abs to CD Markers » Anti -4-1BB Ligand (TNFSF9, CD137, CDw137, ILA, MGC2172, T-cell, 4-1BB homolog, T-cell antigen ILA, Tumor necrosis factor receptor superfamily member 9 precursor) (Biotin)

Anti -4-1BB Ligand (TNFSF9, CD137, CDw137, ILA, MGC2172, T-cell, 4-1BB homolog, T-cell
antigen ILA, Tumor necrosis factor receptor superfamily member 9 precursor) (Biotin)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B FC
4-1BB, also known as CD137, is a type I transmembrane protein belonging to the TNF
receptor superfamily (TNFRSF9). It is expressed on T cells, NK cells, monocytes,
neutrophils, dendritic cells, and eosinophils. The ligand for 4-1BB, 4-1BBL, is a TNF
ligand superfamily member (TNFSF9) expressed on the surfaces of activated antigen
presenting cells and T and B lymphoma cell lines. 4-1BB transduces a T cell
costimulatory signal to promote survival, proliferation, cytokine production, and effector
functions. On dendritic cells, 4-1BB ligation enhances cytokine production and
upregulates expression of B7-1 and B7-2 costimulatory molecules.
Catalog #0004-01Q
ApplicationsSuitable for use in Flow Cytometry and Western Blot. Other applications not tested.
Recommended DilutionFlow Cytometry: 3-10ug/ml/10
Western Blot: 0.1-0.2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~50ug/ml
FormSupplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS with BSA. Reconstitute with 40-50% glycerol, PBS.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant human 4-1BB Ligand aa71-254.
SpecificityRecognizes human 4-1BB Ligand/TNFSF9.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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