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You are here:Home » Growth Factors, Cytokines » Growth Factors-4-1 BB » 4-1 BB Receptor, Recombinant, Human (CD137, 4-1BB Ligand Receptor, TNFRSF9, CDw137, ILA, MGC2172, T-cell antigen 4-1BB homolog)

4-1 BB Receptor, Recombinant, Human (CD137, 4-1BB Ligand Receptor, TNFRSF9, CDw137, ILA,
MGC2172, T-cell antigen 4-1BB homolog)

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Specifications

Human 4-1BB Receptor (4-1BBR) is an inhibitor of 4-1BBL and can block 4-1BBL bioactivity. Human 4-1BBR is a 17.7kDa protein consisting of 167 amino acid residues.
Catalog #0004-02B
Source E. coli
Purity 98% by SDS-PAGE and HPLC analyses
Endotoxin 0.1ng/ug (1EU/ug).
Biological Activity Determined by its inhibitory effect of the 4-1BBL mediated stimulation of IL-8 production by human PBMC (peripheral blood mononuclear cells). About 90% of inibition was seen using a concentration of 1ug for both 4-1BBL and 4-1BBR.
Reconstitution We recommend a quick spin followed by reconsitution in water to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
Storage and Stability The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted 4-1BBL should be stored in working aliquots at -20°C.
AA Sequence MERTRSLQDP CSNCPAGTFC DNNRNQICSP CPPNSFSSAG GQRTCDICRQ CKGVFRTRKE CSSTSNAECD CTPGFHCLGA GCSMCEQDCK QGQELTKKGC KNCCFGTFND QKRGICRPWT NCSLDGKSVL VNGTKERDVV CGPSPADLSP GASSVTPPAP AREPGHS
Country of Origin USA
Molecular Weight17.7kDa
SourceE. coli
FormThe sterile ltered solution was lyophilized from 0.3X PBS.
Important NoteThis product is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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