Anti -14-3-3 epsilon (YWHAE, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase
Activation Protein, epsilon Polypeptide, 14-3-3E, 14-3-3 Protein epsilon, FLJ45465,
FLJ53559, KCIP-1, MDCR, MDS)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
B |
|
| Catalog # | 0014-04C | | Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimers, thus rendering 14-3-3 as a key multifunctional regulatory molecule. 14-3-3 isomers have been implicated in several neurological disorders | for example isoforms gamma, epsilon and beta are expressed in the cerebrospinal fluid of Creutzfeldt-Jakob patients, but not patients suffering from other neurological conditions such as Alzheimer's. | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:500 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Jurkat Cell Lysate. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 10F620 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid with 0.1% sodium azide. | | Purity | Ascites | | Immunogen | Synthetic peptide corresponding to rat 14-3-3 epsilon (aa 208-244). | | Specificity | Recognizes human 14-3-3. Sequence homology: rat, sheep. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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