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17-(Allylamino) Geldanamycin
17-(Allylamino) Geldanamycin
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| Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2. | | | Catalog # | 001807 | | Form | Dark Purple Solid | | Melting Point | >194°C (dec.) | | Solubility | Chloroform, DMSO, Methanol | | CAS Number | 75747-14-7 | | Molecular Formula | C31H43N3O8 | | Molecular Weight | 585.69 | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. | | Alternate names | 17-Demethoxy-17-(2-propenylamino)geldanamycin; 17-(Allylamino)-17-demethoxygeldanamycin; 17-(Allylamino)-17-desmethylgeldanamycin; 17-Demethoxy-17-allylaminogeldanamycin; 17AAG; CP 127374; KOS 953; NSC 330507; Tanespimycin; 17-AAG |
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