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You are here:Home » Biochemicals » Biochem-Inhibitors » 17-(Allylamino) Geldanamycin

17-(Allylamino) Geldanamycin

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Specifications

Potent inhibitor of heat shock protein 90 (Hsp90). 17-AAG is a less toxic analog than Geldanamycin. It induces apoptosis and displays antitumor effects. 17-AAG inhibits the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2.
Catalog #001807
FormDark Purple Solid
Melting Point>194°C (dec.)
SolubilityChloroform, DMSO, Methanol
CAS Number75747-14-7
Molecular FormulaC31H43N3O8
Molecular Weight585.69
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Alternate names17-Demethoxy-17-(2-propenylamino)geldanamycin; 17-(Allylamino)-17-demethoxygeldanamycin; 17-(Allylamino)-17-desmethylgeldanamycin; 17-Demethoxy-17-allylaminogeldanamycin; 17AAG; CP 127374; KOS 953; NSC 330507; Tanespimycin; 17-AAG


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