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You are here:Home » Biochemicals » Biochem-Protein Kinase Activators & Inhibitors » CDDO Methyl Ester

CDDO Methyl Ester


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CDDO Methyl Ester is a synthetic triterpenoid that inhibits I B kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor B-regulated gene products in human leukemic cells. CDDO Methyl Ester is a novel therapeutic agent in the treatment of acute myeloid leukemia and in the treatment of pancreatic cancer as well as other forms of cancer.
Catalog #005841
FormWhite to Off-White Solid
Melting Point215-219°C
SolubilityChloroform, Methanol (Sparingly)
CAS Number218600-53-4
Molecular FormulaC32H43NO4
Molecular Weight505.69
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Alternate names2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic Acid Methyl Ester; Bardoxolone Methyl; CDDO-Me; Methyl 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oate; NSC 713200; RTA 402;

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