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You are here:Home » Biochemicals » Biochem-Neurochemicals » CP-154526 Hydrochloride

CP-154526 Hydrochloride


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A selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1). It blocks CRF-induced adenylate cyclase activation and attenuates activation of the HPA axis by CRF. It displayed anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant.
Catalog #007087
FormPale Yellow Solid
Melting Point167-169°C
SolubilityDMSO, Methanol
Pfizer Compound
CAS Number257639-98-8
Molecular FormulaC23H33ClN4
Molecular Weight400.99
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
Alternate namesN-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Hydrochloride

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