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You are here:Home » Biochemicals » Biochem-Phosphorylating and Phosphitylating » Cyclophosphamide Monohydrate

Cyclophosphamide Monohydrate

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Specifications

It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.
Catalog #007349
Melting Point44-45°C
SolubilityChloroform
Method for Determining IdentityProton NMR Spectroscopic and Mass Spectrometric Analysis
Water Content7.0%
TLC ConditionsSiO2; Dichloromethane: Methanol = 9:1; Visualized with UV, Ninhydrin and KMnO4; Single spot; Rf=0.45
Storage and StabilityMay be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and HazardsAll products should be handled by qualified personnel only, trained in laboratory procedures.
CAS Number6055-19-2
Molecular FormulaC7H17Cl2N2O3P
Molecular Weight279.1
Purity~90%
FormSupplied as a white solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesN,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide Monohydrate; Cycloblastin; Cyclostin; Cytoxan; Endoxan; Genoxal; Hexadrin; Mitoxan; NSC 26271;


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