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Specifications

It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.
Catalog #	007349
Melting Point	44-45°C
Solubility	Chloroform
Method for Determining Identity	Proton NMR Spectroscopic and Mass Spectrometric Analysis
Water Content	7.0%
TLC Conditions	SiO2; Dichloromethane: Methanol = 9:1; Visualized with UV, Ninhydrin and KMnO4; Single spot; Rf=0.45
Storage and Stability	May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Toxicity and Hazards	All products should be handled by qualified personnel only, trained in laboratory procedures.
CAS Number	6055-19-2
Molecular Formula	C7H17Cl2N2O3P
Molecular Weight	279.1
Purity	~90%
Form	Supplied as a white solid.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide Monohydrate; Cycloblastin; Cyclostin; Cytoxan; Endoxan; Genoxal; Hexadrin; Mitoxan; NSC 26271;