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You are here:Home » Biochemicals » Biochem-Mycotoxins » Deoxynivalenol

Deoxynivalenol

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Specifications

Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-mediated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF- B into the nucleus.
Catalog #008132
SolubilityChloroform, DMSO, Ethanol
CAS Number51481-10-8
Molecular FormulaC H O
Molecular Weight296.32
SourceSynthetic
FormWhite to Off-White Solid
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names(3 ,7 )-12,13-Epoxy-3,7,15-trihydroxytrichothec-9-en-8-one; 4-Deoxynivalenol; 4-Desoxynivalenol; DON; Dehydronivalenol; NSC 269144; Vomitoxin


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