USBio Logo

020637 Ribavirin 5’-Triphosphate Trisodium Salt CAS: 63142-71-2

Specifications
References
CAS Number
63142-71-2
Grade
Highly Purified
Molecular Formula
C8H15N4O14P3 (free acid)
Molecular Weight
483.98
EU Commodity Code
38220090
Shipping Temp
Blue Ice
Storage Temp
-20°C
1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate, Sodium salt; [[(2R,3S,4R,5R)-5-(3-carbamoyl-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

A metabolite of Ribavirin.

Concentration
10-11mM
Synonyms
1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate, Sodium salt
CAS No
63142-71-2
Molecular Formula
C8H15N4O14P3 (free acid)
Molecular Weight
483.98 (free acid)
Appearance
White to off-white solid
Purity
≥95% (HPLC)
Spectroscopic Properties
λmax 230 nm, ε 3.6 L mmol-1 cm-1 (Tris-HCl pH 7.5)
pH
7.5 ±0.5
Storage and Stability
Store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
References
Allen, L.B., et al.: J. Med. Chem., 21, 742 (1978), Zimmerman, T., et al.: Biochem. Pharmacol., 27, 709|Kiso et al. (2010) T-705 (favipiravir) activity against lethal H5N1 influenza A viruses. Proc. Natl. Acad. Sci. USA. 107 (2):882.||Maag et al. (2001) Hepatitis C virus RNA-dependent RNA polymerase (NS5B) as a mediator of the antiviral activity of ribavirin. J. Biol. Chem. 276 (49):46094.||Lanford et al. (2001) Ribavirin induces error-prone replication of GB virus B in primary tamarin hepatocytes. J. Virol. 75 (17):8074.||Crotty et al. (2000) The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen. Nat. Med. 6 (12):1375.||Ulrich et al. (2000) Towards the engineering of an orthogonal protein kinase/nucleotide triphosphate pair. Tetrahedron 56 (48):9495.||Hong et al. (1999) Direct antiviral activity of ribavirin: Hepatitis C virus NS5B polymerase incorporates ribavirin triphosphate into nascent RNA products. Hepatology 30 (4):773 Part 2 Suppl. S.
USBio References
No references available
Pricing
Order
Proceed to Checkout
Cart Summary
ProductSizeListYour PriceQtyExt Price
Subtotal:Subtotal:
Subtotal:Subtotal:
Total Coupon Savings:Total Coupon Savings:()
Your cart is currently empty.
- Coupon Code
Recently Viewed
  • Contact Us

    Visit our technical library or contact our support staff to answer your questions.

    Telephone:
    1-800-520-3011

    Library | Contact

    Distributors

    For customers outside of the United States, please use one of our many distributors.

    View Distributors

    Payment Methods

    We accept the following payment methods as well as pay-by-invoice.

    MasterCard Visa PayPal
    © 2023-2024 United States Biological - All Rights Reserved