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Talmapimod
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| Talmapimod is a p38 mitogen-activated protein (MAP) kinase inhibitor. Talmapimod reduced human myeloma cell growth in vivo both at early and advanced phases of the disease in mouse xenograft models. Talmapimod that blocks tumor necrosis factor- , interleukin-1 , and cyclooxygenase-2 synthesis in patients with active rheumatoid arthritis (RA). | | | Catalog # | 021241 | | | | CAS Number | 309913-83-5 | | Molecular Formula | C27H30ClFN4O3 | | Molecular Weight | 513 | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. | | Alternate names | 6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl- -oxo-1H-indole-3-acetamide; SCIO 469; Scios 469; |
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