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You are here:Home » Antibodies » Abs to Thioredoxin » Anti -Thioredoxin (Trx, ATL-derived Factor, ADF, Surface-associated Sulphydryl Protein, SASP, TXN, TRDX, TRX, TRX1) (FITC)

Anti -Thioredoxin (Trx, ATL-derived Factor, ADF, Surface-associated Sulphydryl Protein,
SASP, TXN, TRDX, TRX, TRX1) (FITC)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
Catalog #029384
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in 0.01M PBS, PH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with fluorescein isothiocyanate (FITC).
PurityPurified by ammonium sulfate precipitation.
ImmunogenRecombinant corresponding to human Thioredoxin.
SpecificityRecognizes human Thioredoxin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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