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You are here:Home » Antibodies » Abs to Centrosomal Proteins » Anti -Cep63 (Centrosomal Protein of 63kD, CEP63)

Anti -Cep63 (Centrosomal Protein of 63kD, CEP63)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IC
Centrosomal protein 63 serves an ATM and ATR substrate for spindle assembly activation following chromosomal breakage. It is shown that inactivation of the CEP63 gene in avian DT40 cells impairs spindle assembly and prevents ATM- and ATR-dependent effects on mitosis. Cep63 is also reported to bind to and recruit Cdk1 to centrosomes and is thought to be involved the regulation mitotoic entry, centrosome amplification, and genome maintentance.
Catalog #029443
ApplicationsSuitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:500
Optimal dilutions to be determined by the researcher.
Positive ControlHEK 293 cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to human Cep63.
SpecificityRecognizes human Cep63. Species Crossreactivity: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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