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You are here:Home » Antibodies » Abs to Enzymes, Acyltransferase » Anti -Cholesterol Acyltransferase 1 (Sterol O-acyltransferase 1, Acyl-coenzyme A:cholesterol Acyltransferase 1, ACAT-1, SOAT1, ACACT, ACACT1, ACAT, ACAT1, SOAT, STAT)

Anti -Cholesterol Acyltransferase 1 (Sterol O-acyltransferase 1, Acyl-coenzyme
A:cholesterol Acyltransferase 1, ACAT-1, SOAT1, ACACT, ACACT1, ACAT, ACAT1, SOAT, STAT)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Cholesterol acyltransferase 1 is mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA and plays a significant role in ketone body metabolism. Defects in the gene encoding ACAT1 are associated with the alpha-methylacetoaceticaciduria disorder,an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. Recent studies suggests that ACAT1 may be a therapeutic target for treating certain forms of Alzeheimer's disease.
Catalog #029444
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.05ug/ml
Immunohistochemistry: 1:1000
Optimal dilutions to be determined by the researcher.
Positive ControlCaco-2 cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic linear peptide corresponding to human Cholesterol acyltransferase 1 (KLH).
SpecificityRecognizes human Cholesterol Acyltransferase 1. Species sequence homology: Rhesus macaque, chimpanzee, rat, mouse (93%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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