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You are here:Home » Antibodies » Abs to Tumor Suppressors » Anti -Dab2, CT (Disabled Homolog 2, DOC-2, Differentially-expressed Protein 2, DOC2)

Anti -Dab2, CT (Disabled Homolog 2, DOC-2, Differentially-expressed Protein 2, DOC2)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IC FC
Disabled-2 is a component of the CSF-1 signal transduction pathway. Dab2 is involved in the regulation of cytoskeleton based functions by regulating cell positioning, inducing marcrophage adhesion, or regulation of protein trafficking of endocytosis involved proteins. Dab2 has been implicated in regulating the homeostasis of epithelial differentiation, where Dab2 is involved in endodermal cell formation, differentiation, and organization. Dab2 mRNA expression is common in normal ovarian epithelia cells but low or lack of expression is seen in ovarian carcinoma cell lines.
Catalog #029451
ApplicationsSuitable for use in Flow Cytometry, Western Blot, Immunoprecipitation and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:2000
Immunocytochemistry: 1:100-1:250
Immunoprecipitation: 1:20
Flow Cytometry: 1:50
Optimal dilutions to be determined by the researcher.
Positive ControlHuman pancreas tissue lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No13A171
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.01% sodium azide, 0.05% BSA, 40% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to human Dab2 at C-terminal.
SpecificityRecognizes human Dab2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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