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You are here:Home » Antibodies » Antibodies-Disease Markers » Anti -DSCR3 (Down Syndrome Critical Region Protein 3, Down Syndrome Critical Region Protein A, DCRA, DSCRA)

Anti -DSCR3 (Down Syndrome Critical Region Protein 3, Down Syndrome Critical Region
Protein A, DCRA, DSCRA)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Trisomy of human chromosome 21 result in patients with Down's syndrome, which is a complex developmental and neurodegenerative disease that is characterized with abnormal morphological features, hypotonia, and mental retardation. The DSCR3 gene is found in this region. DSCR3 expresses Down syndrome critical region protein 3, which is reportedly expressed in many studied tissues. While it is suggested that this protein is involved in neuroexcitation and in cellular signaling, further study is still required to elucidate its role and mechanism of action.
Catalog #029458
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5ug/ml
Immunohistochemistry: 1:200
Optimal dilutions to be determined by the researcher.
Positive ControlA549 cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic linear peptide corresponding to human DSCR3 (KLH).
SpecificityRecognizes human DSCR3. Species sequence homology: Rat and mouse (92%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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