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You are here:Home » Antibodies » Abs to Connexin, Junction Proteins » Anti -JAM-A (Junctional Adhesion Molecule A, Junctional Adhesion Molecule 1, JAM-1, CD321, F11r, Jam1, Jcam, Jcam1)

Anti -JAM-A (Junctional Adhesion Molecule A, Junctional Adhesion Molecule 1, JAM-1, CD321,
F11r, Jam1, Jcam, Jcam1)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified IP IC FC
Functional adhesion molecule A is found in endothelial and epithelial tight junctions and is involved in the inflammatory enlistment of mononuclear cells containing LFA-1. JAM-A is linked to atherogenesis, platelet activation, transmigration of leukocytes and angiogenesis. JAM-A is also found to be important in the development of many different organ systems, and is mostly expressed in the epithelial parts and the embryonic vasculature. JAM-A is indicated to play a role in epithelial permeability, inflammation and proliferation in the intestine, aiding in homeostasis.
Catalog #029519
ApplicationsSuitable for use in Flow Cytometry, Immunoprecipitation and Immunocytochemistry. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:1000
Optimal dilutions to be determined by the researcher.
Positive ControlbEnd.3 cells
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2bk
Clone No13A203
HostRat
SourceMouse
ConcentrationNot determined
FormSupplied as a liquid in PBS. No preservative added.
PurityPurified by Protein G affinity chromatography.
ImmunogenH5V murine heart capillary endothelial cells.
SpecificityRecognizes mouse JAM-A.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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