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You are here:Home » Antibodies » Antibodies-Connexin, Junction Proteins » Anti -JAM-C (Junctional Adhesion Molecule C, JAM-2, Junctional Adhesion Molecule 3, JAM-3)

Anti -JAM-C (Junctional Adhesion Molecule C, JAM-2, Junctional Adhesion Molecule 3, JAM-3)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Junctional adhesion molecule C is an adhesion molecule found at endothelial intracellular junctions that plays a role in leukocyte transendothelial migration and other inflammatory events. JAM-C seems to be important in the pathophysiology of pancreatitis and therefore could be a promising clinical target. JAM-C expression has been shown to be increased when T lymphocytes are activated. Research has shown that controlling JAM-C may also be a way of controlling pathological angiogenesis.
Catalog #029520
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.05ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman brain tissue lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic linear peptide corresponding to the cytoplasmic domain of human JAM-C (KLH).
SpecificityRecognizes human JAM-C. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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