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You are here:Home » Antibodies » Abs to Extracellular Matrix Proteins » Anti -MFAP-2 (Microfibrillar-associated Protein 2, Microfibril-associated Glycoprotein 1, MAGP, MAGP-1, MAGP1, MFAP2)

Anti -MFAP-2 (Microfibrillar-associated Protein 2, Microfibril-associated Glycoprotein 1,
MAGP, MAGP-1, MAGP1, MFAP2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Along with elastin, elaunin, oxytalan, and elastin-associated proteins fibrillin-1, microfibrillar-associated glycoprotein-1 (MAGP or MFAP-2) can be found within the juxtacanalicular tissue of the inner and outer walls and within the collector channel walls of human eyes perfused at low and high pressure, among other certain human tissues. MAGP-1 (MFAP-2) is shown to play a significant role in the support and distensibility of the juxtacanalicular region of these collector channels. It is also reported to inhibit LTB-1 binding to fibrillin-1, stimulate the phosphorylation of Smad2, and thereby mediate the subsequent extracellular deposition of latent TGFbeta.
Catalog #029537
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml
Immunohistochemistry: 1:500
Optimal dilutions to be determined by the researcher.
Positive ControlHuman kidney tissue lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic linear peptide corresponding to human MFAP-2 (MAGP) (KLH).
SpecificityRecognizes human MFAP-2. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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