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Anti -MFAP5 (Microfibrillar-associated Protein 5, MFAP-5, MP25, Microfibril-associated Glycoprotein 2, MAGP-2, MAGP2)
Anti -MFAP5 (Microfibrillar-associated Protein 5, MFAP-5, MP25, Microfibril-associated
Glycoprotein 2, MAGP-2, MAGP2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Microfibril-associated protein 2, also known as microfibrillar associated protein 5, is a multifunctional secreted protein that acts as a promoter of tumor cell survival and angiogenesis. Through alphaVbeta3 integrin-mediated signaling, it is suggested that MAGP2 may provide a potential mechanistic link between MAGP2 and angiogenesis, as well as patient survival. Based on a high level of homology between MAGP (MFAP-2) and MAGP-2, both proteins are shown to bind to and activate Notch-1, as well as mediate the subsequent release of the Notch-1 extracellular domain. | | | Catalog # | 029538 | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human skeletal muscle tissue lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic linear peptide corresponding to human MFAP5 (KLH). | | Specificity | Recognizes human MFAP5. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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