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You are here:Home » Antibodies » Abs to Enzymes, Ribonuclease » Anti -PARN (Poly(A)-specific Ribonuclease PARN, Deadenylating Nuclease, Deadenylation Nuclease, Polyadenylate-specific Ribonuclease, DAN)

Anti -PARN (Poly(A)-specific Ribonuclease PARN, Deadenylating Nuclease, Deadenylation
Nuclease, Polyadenylate-specific Ribonuclease, DAN)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Highly Purified B IC
Poly(A) ribonuclease (PARN) is a exoribonuclease responsible for the deadenylation of mRNA. This protein is constitutively expressed in virtually all mammalian tissues. With a critical role in the post-transcriptional control of gene expression PARN consists of two RNA-binding domains and one catalytic domain. Although PARN has a preference for poly(A), data suggests the protein can also degrade poly(U).
Catalog #029573
ApplicationsSuitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml
Immunocytochemistry: 1:500
Optimal dilutions to be determined by the researcher.
Positive ControlA431 cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgMk
Clone No13A213
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.05% sodium azide.
PurityPurified by Ion Exchange chromatography.
ImmunogenSynthetic linear peptide corresponding to human PARN.
SpecificityRecognizes human PARN.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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