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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -PRDM12 (PR Domain Zinc Finger Protein 12, PR Domain-containing Protein 12, PFM9)

Anti -PRDM12 (PR Domain Zinc Finger Protein 12, PR Domain-containing Protein 12, PFM9)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IC
Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger gene RIZ1 is a tumor suppressor gene and the founding member of the PR domain family. PRDM12 (PR domain zinc finger protein 12) also acts as a tumor suppressor and is linked to the pathogenesis of chronic myeloid leukemia. PRDM12 is also thought to play a role in transcriptional regulation.
Catalog #029587
ApplicationsSuitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 3ug/ml
Immunocytochemistry: 1:500
Optimal dilutions to be determined by the researcher.
Positive ControlHuman liver tissue lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenSynthetic linear peptide corresponding to human PRDM12. Conjugated to KLH.
SpecificityRecognizes human PRDM12. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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