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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -RAB25 (Ras-related Protein Rab-25, CATX-8, CATX8)

Anti -RAB25 (Ras-related Protein Rab-25, CATX-8, CATX8)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Ras-related protein Rab-25 is a GTP-binding protein belonging to the Rab family of proteins. RAB25 has been observed to be expressed in kidney, lung and gastrointestinal mucosa, with exclusive expression in epithelial cells. This specific expression has led to the implication that RAB25 has a role as a regulator for vesicular transport associated with epithelia. RAB25 is potentially a selective regulator for transcytotic pathways and apical recycling. Several recent studies have observed a loss of RAB25 in breast cancer tissue and cell lines, and have suggested a potential role for RAB25 as a regulator for Ras induced tumorigenesis.
Catalog #029594
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.05ug/ml
Immunohistochemistry: 1:600
Optimal dilutions to be determined by the researcher.
Positive ControlMCF7 cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
Concentration~1mg/ml
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7.4,150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic linear peptide corresponding to human RAB25 (KLH).
SpecificityRecognizes human RAB25. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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