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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -Rac1 (Ras-related C3 Botulinum Toxin Substrate 1, Cell Migration-inducing Gene 5 Protein, MGC111543, MIG5, p21-Rac1, Ras-like Protein TC25, TC25, TC-25) (FITC)

Anti -Rac1 (Ras-related C3 Botulinum Toxin Substrate 1, Cell Migration-inducing Gene 5
Protein, MGC111543, MIG5, p21-Rac1, Ras-like Protein TC25, TC25, TC-25) (FITC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Rac1 is a member of a RhoGTPase subfamily (Rac1-Rac4) that transduces extracellular signals from G-coupled protein receptors (GPCR), integrins and growth factor receptors to effector molecules that modulate multiple signaling pathways. While Rac1 supports the activation of MAPkinase pathways and gene activation, itís most important functions include the regulation of cytoskeletal structures. Together with Rho (regulator of stress fibers) and Cdc42 (regulator of filopodia), Rac modulates the formation of focal adhesion (FA) complexes; membrane ruffles and lamellipodia that contribute to important cell functions related to cell attachment and movement.
Catalog #029596
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionsFlow Cytometry: 1:5 with PBS.
Optimal dilutions to be determined by the researcher.
Positive ControlB35 cells
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. FITC conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No13A216
HostMouse
ConcentrationNot Determined
FormSupplied as a liquid in PBS, 15mg/ml BSA.. 0.1% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant protein corresponding to full length human Rac1 (NP_008839). Species Sequence Homology: mouse and human
SpecificityRecognizes rat Rac1. Slight reactivity with Rac2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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