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You are here:Home » Antibodies » Antibodies-Signal Transduction » Anti -Tensin-3 (TNS3, Tensin-like SH2 Domain-containing Protein 1, Tumor Endothelial Marker 6, TEM6, TENS1, TPP)

Anti -Tensin-3 (TNS3, Tensin-like SH2 Domain-containing Protein 1, Tumor Endothelial
Marker 6, TEM6, TENS1, TPP)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IC
Tensin-3 is a member of the Tensin family of proteins that serve as a connection between the cytoskeleton and extracellular matrix. Because of this link, Tensinís are commonly thought to regulate signaling for the shape of the cell and motility. Tensin-3 localizes in the cell cytoplasm and has been shown to be significantly decreased in many different human cancer cell lines. Higher expression levels of Tensin-3 were also found to be associated with longer survival. Tensin-3 has also been found to be highly expressed in functioning thyroid follicular adenomas while expression is significantly lower in non-functioning thyroid follicular adenomas, which seems to imply that Tensin-3 has an important role in basic thyroid function.
Catalog #029622
ApplicationsSuitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml
Immunocytochemistry: 1:500
Optimal dilutions to be determined by the researcher.
Positive ControlHuman kidney tissue lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic linear peptide corresponding to human Tensin-3 (KLH).
SpecificityRecognizes human Tensin-3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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