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Anti -Tensin-3 (TNS3, Tensin-like SH2 Domain-containing Protein 1, Tumor Endothelial Marker 6, TEM6, TENS1, TPP)
Anti -Tensin-3 (TNS3, Tensin-like SH2 Domain-containing Protein 1, Tumor Endothelial
Marker 6, TEM6, TENS1, TPP)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IC |
|
| Tensin-3 is a member of the Tensin family of proteins that serve as a connection between the cytoskeleton and extracellular matrix. Because of this link, Tensin’s are commonly thought to regulate signaling for the shape of the cell and motility. Tensin-3 localizes in the cell cytoplasm and has been shown to be significantly decreased in many different human cancer cell lines. Higher expression levels of Tensin-3 were also found to be associated with longer survival. Tensin-3 has also been found to be highly expressed in functioning thyroid follicular adenomas while expression is significantly lower in non-functioning thyroid follicular adenomas, which seems to imply that Tensin-3 has an important role in basic thyroid function. | | | Catalog # | 029622 | | Applications | Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1ug/ml | | Immunocytochemistry: 1:500 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human kidney tissue lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic linear peptide corresponding to human Tensin-3 (KLH). | | Specificity | Recognizes human Tensin-3. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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