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ARL14, Recombinant, Human, aa1-192, His-tag (ADP-ribosylation Factor-like Protein 14, ADP-ribosylation Factor 7, ARF7)
ARL14, Recombinant, Human, aa1-192, His-tag (ADP-ribosylation Factor-like Protein 14,
ADP-ribosylation Factor 7, ARF7)
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| ARL14, is a developmentally regulated member of the ADP-ribosylation factor/ARF-like protein (ARF/ARL) family of Ras-related GTPases. MHC class II molecules (MHC-II) present peptides to T helper cells to facilitate immune responses and are strongly linked to autoimmune diseases. MHC-II transport was controlled by the GTPase ARL14/ARF7, which recruits the motor myosin 1E via an effector protein ARF7EP. | | | Catalog # | 029647 | | Source | Recombinant corresponding to aa1-192 from human ARL14, fused to His-tag at N-terminal expressed in E.coli. | | AA Sequence | MGSSHHHHHH SSGLVPRGSH MGSLGSKNPQ TKQAQVLLLG LDSAGKSTLL YKLKLAKDIT TIPTIGFNVE MIELERNLSL TVWDVGGQEK MRTVWGCYCE NTDGLVYVVD STDKQRLEES QRQFEHILKN EHIKNVPVVL LANKQDMPGA LTAEDITRMF KVKKLCSDRN WYVQPCCALT | | GEGLAQGFRK LTGFVKSHMK SRGDTLAFFK QN | | Molecular Weight | ~23.8kD (MALDI-TOF) | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | ~23.8kD | | Source | E.coli | | Purity | ~90% (SDS-PAGE) | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 2mM DTT, 40% glycerol, 200mM sodium chloride, 1mM EDTA. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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