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You are here:Home » Antibodies » Abs to Lipoproteins » Anti -Apoa1 (Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1)

Anti -Apoa1 (Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
ApoA1 is a 29kD protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA1 which is found exclusively in HDL has a unique ability to capture and solubilize free cholesterol. This ApoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is thought to inhibit atherogenesis. For this reason HDL is also known as the "good cholesterol." The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of ApoA-I (called ApoA1 Milano). Rat ApoA1 s a 27.4kD protein of 235aa residues.
Catalog #029719
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.01% thimerosal, 30% glycerol.
PurityPurified by affinity chromatography.
ImmunogenRecombinant protein corresponding to rat ApoA1 expressed in E. coli.
SpecificityRecognizes rat ApoA1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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