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You are here:Home » Antibodies » Abs to Interferon » Anti -IFNG (Interferon gamma, IFN-gamma, Immune Interferon)

Anti -IFNG (Interferon gamma, IFN-gamma, Immune Interferon)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B N
IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigenspecific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Murine IFN-gamma is a 15.6kD protein containing 134aa residues.
Catalog #029802
ApplicationsSuitable for use in Western Blot, ELISA and Neutralization. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-1ug/ml
ELISA: 2-3ug/ml
Neutralization: 0.2-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.02% thimerosal, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant protein corresponding to mouse IFN-gamma expressed in E.coli.
SpecificityRecognizes mouse IFN-gamma.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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