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You are here:Home » Antibodies » Abs to Interleukin » Anti -Il18 (Interleukin-18, IL-18, Interferon gamma-inducing Factor, IFN-gamma-inducing Factor, Interleukin-1 gamma, IL-1 gamma, Igif)

Anti -Il18 (Interleukin-18, IL-18, Interferon gamma-inducing Factor, IFN-gamma-inducing
Factor, Interleukin-1 gamma, IL-1 gamma, Igif)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP N
IL-18 (IFN-gamma-inducing factor, IGIF) is a novel proinflammatory cytokine that augments natural killer (NK) activity in spleen cells. It also has other biological properties such as activation of NF-kB, stimulation of Fas ligand expression, induction of CC and CXC chemokines. IL-18 increases production of competent HIV. IL-18 is related to the IL-1 family. One of the IL-18 receptor chains is the IL-1 receptor-related protein, a member of the IL-1R family. Like IL-1b, IL-18 is first synthesized as a leaderless precursor requiring the IL-1b converting enzyme (ICE) for cleavage into an active molecule. IL-18 may play a role in tissue injury in inflammatory reactions.
Catalog #029817
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Neutralization. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-4ug/ml
Neutralization: 2-5ug/ml
Immunoprecipitation: 2-5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 1% BSA, 0.02% thimerosal, 50% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to mouse IL-18.
SpecificityRecognizes mouse IL-18.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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