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Anti -Il18 (Interleukin-18, IL-18, Interferon gamma-inducing Factor, IFN-gamma-inducing Factor, Interleukin-1 gamma, IL-1 gamma, Igif)
Anti -Il18 (Interleukin-18, IL-18, Interferon gamma-inducing Factor, IFN-gamma-inducing
Factor, Interleukin-1 gamma, IL-1 gamma, Igif)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP N |
|
| IL-18 (IFN-gamma-inducing factor, IGIF) is a novel proinflammatory cytokine that augments natural killer (NK) activity in spleen cells. It also has other biological properties such as activation of NF-kB, stimulation of Fas ligand expression, induction of CC and CXC chemokines. IL-18 increases production of competent HIV. IL-18 is related to the IL-1 family. One of the IL-18 receptor chains is the IL-1 receptor-related protein, a member of the IL-1R family. Like IL-1b, IL-18 is first synthesized as a leaderless precursor requiring the IL-1b converting enzyme (ICE) for cleavage into an active molecule. IL-18 may play a role in tissue injury in inflammatory reactions. | | | Catalog # | 029817 | | Applications | Suitable for use in Western Blot, Immunoprecipitation and Neutralization. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5-4ug/ml | | Neutralization: 2-5ug/ml | | Immunoprecipitation: 2-5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Mouse | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.02% thimerosal, 50% glycerol. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to mouse IL-18. | | Specificity | Recognizes mouse IL-18. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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