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You are here:Home » Antibodies » Abs to Transcription Factors » Anti -a-Fetoprotein (Alpha Fetoprotein, Alpha-fetoprotein Precursor, AFP, Alpha-1-fetoprotein, Alpha-fetoglobulin, FETA, HPAFP)

Anti -a-Fetoprotein (Alpha Fetoprotein, Alpha-fetoprotein Precursor, AFP,
Alpha-1-fetoprotein, Alpha-fetoglobulin, FETA, HPAFP)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse E B
AFP (alpha-fetoprotein), a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Catalog #029938
ApplicationsWestern Bloting: 1:500-1:2000.
ELISA: Suggested dilution 1:10000.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No13B16
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, 0.03% sodium azide, 50% glycerol.
PurityPurified by Protein G affinity chromatography.
ImmunogenPurified recombinant fragment of human AFP expressed in E. coli.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesalpha-fetoprotein; FETA; HPAFP


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