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APOA5, Antibody Set, BioAssay™
APOA5, Antibody Set, BioAssay™
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| Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum | | | Catalog # | 029960 | | This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits. | | Applications | Western Bloting: 1:500-1:2000. | | Immunofluorescence: 1:200-1:1000. | | ELISA: Suggested dilution 1:10000. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Product Type | Mab | | Isotype | IgG1 | | Clone No | 13B38 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Purified antibody in PBS, 0.03% sodium azide. | | Purity | Purified | | Immunogen | Purified recombinant fragment of human Apoa5 expressed in E. coli. | | Specificity | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | RAP3; APOAV; APOA-V; MGC126836; MGC126838 |
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