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You are here:Home » Antibodies » Abs to Enzymes, Synthase » Anti -ATP-Citrate Lyase (ACLY, ATP Citrate (pro-S) Lyase, ATP Citrate Synthase, Citrate Cleavage Enzyme, CLATP, EC 2.3.3.8)

Anti -ATP-Citrate Lyase (ACLY, ATP Citrate (pro-S) Lyase, ATP Citrate Synthase, Citrate
Cleavage Enzyme, CLATP, EC 2.3.3.8)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse E B IH IC FC
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine.
Catalog #029975
ApplicationsWestern Blot: 1:500-1:2000
Immunohistochemistry: 1:200-1:1000
Immunocytochemistry: 1:50
Flow Cytometry: 1:200-1:400
ELISA: 1:10000
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No13B53
HostMouse
SourceHuman
ConcentrationAs reported
FormPurified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
PurityPurified
ImmunogenPurified recombinant fragment of human ACLY (AA: 306-502 ) expressed in E. coli.
SpecificityHuman, Mouse, Monkey,
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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