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You are here:Home » Antibodies » Abs to Disease Markers » Anti -AURKA (Aurora kinase A)

Anti -AURKA (Aurora kinase A)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse E B IH
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.
Catalog #029979
ApplicationsWestern Bloting: 1:500-1:2000.
Immunohistochemistry: 1:200-1:1000.
ELISA: Suggested dilution 1:10000.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No13B57
HostMouse
SourceHuman
ConcentrationNot determined
FormAscites fluid, 0.03% sodium azide.
PurityAscites
ImmunogenPurified recombinant fragment of human AURKA expressed in E. coli.
SpecificityHuman, Monkey, Rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAIK; ARK1; AURA; BTAK; STK6; STK7; STK15; AURORA2; MGC34538; AURKA


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