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Abs to Ubiquitin Ligases
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Anti -BMI1
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
|
E B IH FC |
|
| Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. | | | Catalog # | 029995 | | Applications | Western Bloting: 1:500-1:2000. | | Immunohistochemistry: 1:200-1:1000. | | Immunofluorescence: 1:200-1:1000. | | Flow cytometry: 1:200-1:400. | | ELISA: Suggested dilution 1:10000. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 13B73 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | Ascites fluid, 0.03% sodium azide. | | Purity | Ascites | | Immunogen | Purified recombinant fragment of human BMI1 expressed in E. coli. | | Specificity | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | PCGF4; RNF51; MGC12685; FLVI2/BMI1 |
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