Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications Monoclonal Mouse E B IH FC

The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
Catalog #	030008
Applications	Western Bloting: 1:500-1:2000.
	Immunohistochemistry: 1:200-1:1000.
	Immunofluorescence: 1:200-1:1000.
	Flow cytometry: 1:200-1:400.
	ELISA: Suggested dilution 1:10000.
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG1
Clone No	13B86
Host	Mouse
Source	Human
Concentration	As reported
Form	Ascites fluid, 0.03% sodium azide.
Purity	Ascites
Immunogen	Purified recombinant fragment of human C-CBL expressed in E. coli.
Specificity	Human, Mouse, Rat
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	CBL; CBL2; NSLL; C-CBL; RNF55