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Specifications

Clone Host Grade Applications Monoclonal Mouse E B IH FC

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
Catalog #	030024
Applications	Western Bloting: 1:500-1:2000.
	Immunohistochemistry: 1:200-1:1000.
	Immunofluorescence: 1:200-1:1000.
	Flow cytometry: 1:200-1:400.
	ELISA: Suggested dilution 1:10000.
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG1
Clone No	13B102
Host	Mouse
Source	Human
Concentration	As reported
Form	Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
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Purity	Purified
Immunogen	Purified recombinant fragment of human CCL2 expressed in E. coli.
Specificity	Human, Mouse, Monkey
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30