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030090 Mouse Anti-CEBPB

Specifications
References
Clone Type
Monoclonal
Host
Mouse
Source
Human
Swiss Prot
P17676
Isotype
IgG1
Clone Number
13B168
Grade
Ascites
Applications
E FC WB
Crossreactivity
Hu
Gene ID
1051
Shipping Temp
Blue Ice
Storage Temp
-20°C
LAP; CRP2; TCF5; IL6DBP; NF-IL6; MGC32080; C/EBP-beta

The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. Tissue specificity: Expressed at low levels in the lung, kidney and spleen.

Applications
Western Bloting: 1:500-1:2000. Flow cytometry: 1:200-1:400. ELISA: Suggested dilution 1:10000. Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Purified recombinant fragment of human CEBPB expressed in E. coli.
Form
Supplied as a liquid, 0.03% sodium azide.
Purity
Ascites
Specificity
Human
References
1. Biochem J. 2009 Dec 14;425(1):215-23.|2. Cell Signal. 2009 Dec;21(12):1918-24. |
USBio References
No references available
Conjugates
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