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You are here:Home » Antibodies » Abs to Carbohydrates, Glycoproteins » Anti -CHIT1 (Chitinase 1, Chitotriosidase)  

Anti -CHIT1 (Chitinase 1, Chitotriosidase)  

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Specifications

Clone Host Grade Applications
Monoclonal Mouse E B
CHIT1:chitinase 1 (chitotriosidase). Chitotriosidase is a 50kD secreted glycoprotein that belongs to glycohydrolase family # 18. It is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
Catalog #030094
ApplicationsWestern Bloting: 1:500-1:2000.
ELISA: Suggested dilution 1:10000.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No13B172
HostMouse
SourceHuman
ConcentrationNot determined
FormAscites fluid, 0.03% sodium azide.
PurityAscites
ImmunogenPurified recombinant fragment of CHIT1 (aa22-137) expressed in E. coli.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesChitotriosidase;CHI3; CHIT; FLJ00314; MGC125322; CHIT1


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