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You are here:Home » Antibodies » Abs to Disease Markers » Anti -EIF2AK3 (Eukaryotic translation initiation factor 2-alpha kinase 3, HsPEK, Pancreatic eIF2-alpha kinase, PEK, PERK)

Anti -EIF2AK3 (Eukaryotic translation initiation factor 2-alpha kinase 3, HsPEK,
Pancreatic eIF2-alpha kinase, PEK, PERK)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse E B
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.
Catalog #030162
ApplicationsWestern Bloting: 1:500-1:2000.
ELISA: Suggested dilution 1:10000.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No13B240
HostMouse
SourceHuman
ConcentrationNot determined
FormAscites fluid, 0.03% sodium azide.
PurityAscites
ImmunogenPurified recombinant fragment of human EIF2AK3 expressed in E. coli.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPEK; WRS; PERK; EIF2AK3


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