Pricing

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Specifications

Clone Host Grade Applications Monoclonal Mouse E B IH

FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Catalog #	030228
Applications	Western Bloting: 1:500-1:2000.
	Immunohistochemistry: 1:200-1:1000.
	ELISA: Suggested dilution 1:10000.
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone Type	Monoclonal
Isotype	IgG1
Clone No	13B306
Host	Mouse
Source	Human
Concentration	Not determined
Form	Ascites fluid, 0.03% sodium azide.
Purity	Ascites
Immunogen	Purified recombinant fragment of human FGR expressed in E. coli.
Specificity	Human,Mouse
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	SRC2; c-fgr; c-src2; p55c-fgr; p58c-fgr