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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -GATA3 (GATA binding protein 3)

Anti -GATA3 (GATA binding protein 3)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse E B IH
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. (provided by RefSeq) Tissue specificity: T-cells and endothelial cells RD: GATA-3 belongs to the GATA family of transcription factors, which bind to the consensus DNA sequence (A/T) GATA (A/G) to control diverse tissue-specific programs of gene expression and morphogenesis. It is widely expressed in mesodermal- and endodermal-derived tissues. GATA-3 has been shown to be an essential regulator for immune cell function, sympathetic neuron development, and the maintenance of the differentiated state in epithelial cells.
Catalog #030261
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:500-1:2000
Immunohistochemistry: 1:200-1:1000
ELISA: 1:10,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No13B339
HostMouse
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid, 0.03% sodium azide.
PurityAscites
ImmunogenPurified recombinant fragment of human GATA3 expressed in E. coli.
SpecificityRecognizes human GATA3 at ~48kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesHDR;MGC2346;MGC5199;MGC5445;GATA3


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