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Specifications

Clone Host Grade Applications Monoclonal Mouse E B IH

Myoglobin (MB), with 154-amino acid protein (about 17kD), is a member of the globin superfamily and expression of myoglobin is highest in skeletal and cardiac muscle. Functionally, myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. Myoglobin is also thought to buffer intracellular O2 concentration when muscle activity increases and to facilitate intracellular O2 diffusion by providing a parallel path that augments simple diffusion of dissolved O2. Furthermore, myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.
Catalog #	030473
Applications	Western Bloting: 1:500-1:2000.
	Immunohistochemistry: 1:200-1:1000.
	ELISA: Suggested dilution 1:10000.
	Optimal dilutions to be determined by the researcher.
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG1
Clone No	13B551
Host	Mouse
Source	Human
Concentration	As reported
Form	Purified antibody in PBS, 0.03% sodium azide.
Purity	Purified
Immunogen	Purified recombinant fragment of Myoglobin expressed in E. coli.
Specificity	Human
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	PVALB; MGC13548; MB