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You are here:Home » Antibodies » Abs to Neurofilament » Anti -NEFH (Neurofilament Heavy Polypeptide, NF-H, 200kD Neurofilament Protein, Neurofilament Triplet H Protein, KIAA0845, NFH)

Anti -NEFH (Neurofilament Heavy Polypeptide, NF-H, 200kD Neurofilament Protein,
Neurofilament Triplet H Protein, KIAA0845, NFH)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse E B IH
Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglian cells. Neurofilaments consist of three major subunits with molecular weights of 68kD, 160kD and 200kD. This antibody will help detect the neurofilament 200kD subunit in normal and uncharacterized tissues.
Catalog #030483
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.
ApplicationsWestern Blot: 1:500-1:2000
Immunohistochemistry: 1:200-1:1000
ELISA 1:10000 proposed
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No13B561
HostMouse
SourceHuman
ConcentrationAs reported
FormPurified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
PurityPurified
ImmunogenPurified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. coli.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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