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You are here:Home » Antibodies » Abs to Osteopontin » Anti -Osteopontin (Bone Sialoprotein 1, SPP-1, Urinary Stone Protein, Uropontin, Nephropontin, Secreted Phosphoprotein 1, SPP1, BNSP, OPN, PSEC0156, ETA-1)

Anti -Osteopontin (Bone Sialoprotein 1, SPP-1, Urinary Stone Protein, Uropontin,
Nephropontin, Secreted Phosphoprotein 1, SPP1, BNSP, OPN, PSEC0156, ETA-1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse E B IH IC
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
Catalog #030512
Osteopontin, also named early T lymphocyte activation protein 1, secreted phosphoprotein, and bone sialoprotein 1, is a secreted acidic phosphorylated glycoprotein originally isolated from bone matrix. It has been shown to bind to different cell types through interactions with various integrins and CD44 variants. It has important functions in bone metabolism and inflammatory processes.
ApplicationsWestern Blot: 1:500-1:2000
Immunohistochemistry: 1:200-1:1000
Immunocytochemistry: 1:200-1:1000
ELISA: 1:10000
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No13B590
HostMouse
SourceHuman
ConcentrationAs reported
FormPurified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer
PurityPurified
ImmunogenPurified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. coli.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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