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You are here:Home » Antibodies » Antibodies-Disease Markers » Anti -Actin, alpha (ACTA1, ACTA, skeletal muscle, Alpha-actin-1)

Anti -Actin, alpha (ACTA1, ACTA, skeletal muscle, Alpha-actin-1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH FC
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Catalog #030740
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications not tested.
Recommended DilutionsWestern Blot: 1:100-1:500
Immunohistochemistry (FFPE): 1:10-1:50
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No337CT30.10.1
HostMouse
SourceHuman
ConcentrationAs Reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant protein corresponding to human Actin, alpha (P68133). Species sequence homology: bovine, chicken, mouse, procine, rabbit and rat
SpecificityRecognizes human Actin, alpha.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesACTA1, ACTA, Actin, alpha skeletal muscle, Alpha-actin-1


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