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You are here:Home » Antibodies » Abs to Disease Markers » Anti -AGT, NT (SERPINA8, Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin I, Angiotensin-2, Angiotensin II, Angiotensin-3, Angiotensin III, Des-Asp[1]-angiotensin II) (AP)

Anti -AGT, NT (SERPINA8, Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin I,
Angiotensin-2, Angiotensin II, Angiotensin-3, Angiotensin III, Des-Asp[1]-angiotensin II)
(AP)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Catalog #030750-AP
ApplicationsSuitable for use in Western Blot, ELISA.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100~1000
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C with the addition of glycerol. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive.
Clone TypeMonoclonal
IsotypeIgG1
Clone No656CT5.8.4
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Alkaline Phosphatase.
PurityPurified by Protein G affinity chromatography.
ImmunogenAGT Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human AGT.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAGT, SERPINA8, Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin I, Angiotensin-2, Angiotensin II, Angiotensin-3, Angiotensin III, Des-Asp[1]-angiotensin II


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